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Three newly discovered coffee compounds facilitate treat diabetes

Studies have consistently shown the positive effects of coffee consumption on type 2 diabetes. From lower mortality and fat loss to synthetic genes that trigger treatment and reduce the risk of the disease in leisurely metabolizers, as well as an overall reduction in the risk of developing it, coffee is a miracle cure for type 2 diabetes. Scientists have now discovered three anti-diabetic compounds in roasted coffee that may be more effective than time-honored anti-diabetes drugs.

As reported SciTechDailyThe study was published in a journal by a team from the Kunming Institute of Botany of the Chinese Academy of Sciences. To do this, researchers broke down roasted Arabica coffee extract into 190 smaller fractions using silica gel chromatography, “a common technique for separating compounds based on how they move through a solid material.” Each fraction was then tested to determine how effectively it blocked the activity of α-glucosidase, an enzyme that breaks down carbohydrates during digestion. Blocking α-glucosidase helps control spikes in blood sugar levels after eating and thus helps treat type 2 diabetes.

Using a heat map of the data, researchers were able to pinpoint the three most biologically lively fractions, leading to the discovery of “three previously unknown diterpene esters named coffee aldehydes A, B, and C.” Each of the three esters has been shown to inhibit α-glucosidase activity more effectively than acarbose, “a clinically prescribed antidiabetic drug commonly used to treat type 2 diabetes.”

In addition to amplifying the positive effects of coffee consumption on people with type 2 diabetes, the findings hold promise for the development of “modern functional food ingredients or coffee-derived nutraceuticals” that will facilitate regulate and treat diabetes.

Either way, this is more good news regarding the well effects of coffee on the body.

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